Dr. rer. nat. Jonathan Dawson
Raum Ex 137
Tel.: +49 (0) 381 498-7075
Fax: +49 (0) 381 498-7081
Development of multi-scale and multi-physics constitutive models for biological systems such as cells and tissues under the influence external fields.
Influence of external electric fields on stem cell differentiation and cell migration.
Mean-field and finite element modelling of dynamical living systems.
Tissue morphogenesis during growth and development.
Biophysics
Living cells are exposed to both endogenous and exogenous fields.
The influence of these fields on the cells, whether isolated or in a tissue, is crucial for many biological processes, such as growth, development and even organ regeneration in living organisms. In vitro studies have shown that the external electric fields influence osteogenic differentiation of human mesenchymal stem cells and osteoblast migration. In growing tissues, inter-cellular transport of growth factor and hormones, which regulate cellular growth, can generate non-trivial stress distributions, important for organ development. I develop multi-scale and multi-physics dynamical models to study these biological processes and predict their outcome in perturbation conditions.
Models are developed using physical tools such as the mean-field theory, particle-based collective dynamics approach, finite-element-method, vertex models, reaction-diffusion theory.
Publications list:
https://scholar.google.de/citations?user=4iWY-8AAAAAJ&hl=en (Google scholar)
- 2018-2019: Scientific researcher - ScreenSYS GmbH, Freiburg im Breisgau, Germany
- 2015-2016: Postdoctoral researcher, Syracuse University, New York, USA
- 2012-2015: Postdoctoral researcher, Max Planck Institute - DS, Göttingen, Germany
- 2008-2012: PhD/Doctoral studies, Max Planck Institute - PKS, Dresden, Germany
- 2003-2007: Bachelor studies in Electronics Engineering, SHUATS (formerly AAI-DU), Allahabad, India
Unique IDs
- ORCID: https://orcid.org/0000-0001-9770-8475
- Scopus Author ID: 5719110151